Abscess: An abscess is a collection of pus caused by a bacterial infection.
Bowel Perforation: Severe inflammation may result in a hole developing anywhere along the gastrointestinal tract which can lead to sepsis; sepsis is very serious and usually requires immediate surgical attention.
Fistulizing disease: According to studies, 35-50% of Crohn’s disease patients develop at least one fistula. Fistulae are complications of Crohn’s disease that follow damage to the lining of the intestines and result in abscesses and abnormal tunnels between the intestine and other organs (e.g., bladder), or out onto the exterior surface of the skin. Many fistulae can develop within the anal and genitourinary areas (scrotum, penis, vulva, vagina, etc.), and are often referred to as perianal disease.
Stricturing disease: Another complication of Crohn’s disease is an intestinal stricture, which is a narrowing of the intestine from severe inflammation. Strictures obstruct contents from passing through the intestine or bowel and can result in intestinal blockages and sometimes bowel perforations.